Sphere of Destruction can refer to:
- Beerus Ball, called by this name in Xenoverse and Heroes.
- Cataclysmic Orb, called by this name in FighterZ, Legends and Kakarot.
- Chaotic Sphere of Destruction, Champa's similarly named technique.
- Enjoy Browning, called "Destruction Ball" in the Collectible Card Game.
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