- Dr. Briefs founds the Capsule Corporation after inventing the revolutionary "Hoi-Poi Capsules".
- The evil scientist Dr. Wheelo schemes of using his advanced science to take over the Earth, restructuring humanity into an obedient cyborg race. However, a freak weather disaster seals him and his entire laboratory within an eternal wall of ice. The people attribute this to divine judgement. Dr. Wheelo’s robotic assistant Dr. Kochin is left behind, and begins searching for a way to free his master.